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Title: | Psychosocial factors and glycemic control in insulin-naïve and insulin-experienced people with type 2 diabetes: a path analysis model |
Authors: | Rokhsareh Aghili Martin Ridderstråle Amir Farshchi Ameneh Ebrahim Valojerdi Zahra Banazadeh3 Mojtaba Malek Maryam Kia Mohammad Ebrahim Khamseh |
Subject: | Diabetes;type 2;Psychosocial;Glycemic control |
Issue Date: | 2017 |
Abstract: | Abstract The purpose of this study was to compare the status of psychosocial factors and glycemic control in insulin-naïve and insulin-experienced people with type 2 diabetes (T2D). In this observational study on people with T2D, demographic, self-care behavior, resources, and affective variables as well as health-related quality of life were assessed and compared in insulin-naïve and insulin-experienced considering the number of oral glucose-lowering drugs (OGLDs). Measured variable path analysis was used to test the association among variables and their effect on HbA1c in both groups. In total, 215 insulinnaïve and 165 insulin-experienced patients were recruited in this study. The mean duration of diabetes was 11.7 ± 7.0 years in insulin-experienced and 6.8 ± 5.4 years in insulin-naïve (p < 0.001). The mean hemoglobin A1c (HbA1c) was significantly higher in insulin-experienced subjects irrespective of the number of OGLDs [68 ± 20 mmol/mol (8.4 ± 1.8%) vs. 56 ± 16 mmol/mol (7.3 ± 1.4%); p < 0.001]. Moreover, insulin-experienced subjects had significantly higher level of diabetes-related distress (2.2 ± 0.9 vs. 1.9 ± 0.8), depression (9.5 ± 5.5 vs. 8.1 ± 5.1), anxiety (18.3 ± 12.0 vs. 15.1 ± 10.5), and lower knowledge of insulin use considering the results of 9-item insulin-use subscale of Michigan diabetes knowledge test (mean 3.9 ± 1.8) compared to insulin-naïve subjects (p < 0.05). Higher levels of distress, depression, and anxiety are found in insulin-experienced people with T2D. Therefore, one should be aware that, at the time of insulin need/initiation, people with T2D have reached a more vulnerable state and this should be taken into consideration when implementing a complex insulin initiation plan. |
URI: | https://link.springer.com/article/10.1007/s13410-017-0581-2 http://dl.iem.iums.ac.ir/handle/Hannan/984 |
Type: | Article |
Appears in Collections: | Diabetes |
Files in This Item:
File | Description | Size | Format | |
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59- Psychosocial factors and glycemic control in insulin-naïve.pdf | 488.7 kB | Adobe PDF | View/Open |
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