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http://dl.iem.iums.ac.ir/handle/Hannan/273| Title: | Leptin;[electronic resource] :;Regulation and Clinical Applications /;edited by Sam Dagogo-Jack, MD. |
| Authors: | D Agogo-J Ack, MD, S Am |
| Subject: | Medicine;Endocrinology;Metabolic diseases;Medicine & Public Health;Endocrinology;Metabolic Diseases;616.4 23;RC648-665.2 |
| Issue Date: | 2015 |
| Publisher: | Springer International Publishing;Imprint Springer, |
| place: | Cham |
| Abstract: | Twenty years after its discovery, recombinant human leptin has been approved by the Food and Drug Administration for the treatment of patients with lipodystrophy. Beginning with a synthesis of the vast body of work on its discovery, dissection of mechani |
| Description: | Printed edition:;9783319099149. |
| Table of Contents: | Discovery of leptin and elucidation of leptin gene expression -- Leptin receptors and mechanism of action -- Leptin interaction with brain orexigenic and anorexigenic pathways -- Measurement of circulating leptin and soluble leptin receptors -- Physiological and hormonal factors that influence leptin production -- Leptin, obesity and leptin resistance -- Leptin and intermediary metabolism: Focus on glucoregulation and lipid metabolism -- Leptin in acute stress -- Leptin and the kidney -- Leptin, immune function, and inflammation -- Leptin and bone -- Leptin, cell cycle, and cancer -- Leptin, the autonomic nervous system, and hypertension -- Dynamic leptin secretion in obesity and diabetes -- Leptin therapy of congenital leptin deficiency -- Leptin therapy in people with normal leptin gene -- Leptin therapy in patients with lipodystrophy and syndromic insulin resistance -- Leptin therapy in women with hypothalamic amenorrhea -- Leptin therapy as a substitute for insulin replacement in experimental models of diabetes: Clinical implications in humans -- Novel combinatorial therapies involving leptin: Opportunities for mechanistic advances and therapeutic translation in human diseases. |
| URI: | http://dl.iem.iums.ac.ir/handle/Hannan/273 |
| ISBN: | 9783319099156 9783319099149 (print) |
| Type: | Book |
| Appears in Collections: | Endocrine System disease |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 9783319099156.pdf | 8.72 MB | Adobe PDF |  View/Open |
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