Endocrine Disrupting Chemicals-induced Metabolic Disorders and Treatment Strategies

Abstract

Metabolic disorders (MDs) are promptly aggregating in the increasing population globally. This is greatly affecting the social and financial status of individuals particularly of developing and/or underdeveloped countries. Unfortunately, specifically these countries are also victims of environmental contaminants and habitual impurities that can be considered as the foremost keystones not only for initiating the occurrence but also for flourishing the progress of MDs. These contaminants include a major contribution of endocrine-disrupting chemicals (EDCs). According to the World Health Organization (WHO), these EDCs are “mostly man-made, found in various materials such as pesticides, metals, additives or contaminants in food, and personal care products” and that “Human exposure to EDCs occurs via ingestion of food, dust, and water, via inhalation of gases and particles in the air, and through the skin.” This accentuates the urge to better comprehend the principal disease mechanisms, which will not only help in eradicating these underpinning causative factors but may also propose targeted therapy for the MDs caused by EDCs. This book entitled “Endocrine-Disrupting Chemicals-induced Metabolic Disorders and Treatment Strategies” is envisioned to first provide an introduction to the endocrine system and MDs followed by a profound discussion on the role of various EDCs and/or sources of EDCs in causing the induction, prevalence, and even progression of MDs. Lastly, in the third part of this book, we have deliberated the potential account of prevention and therapeutic intervention by elaborating the treatment strategies of EDCs-induced metabolic disorders.